Description

PE-22-28 10mg Peptide

PE-22-28 10mg Peptide for sale online at Peptides Link Laboratory.

Buy PE-22-28, a synthetic peptide derived from the neuropeptide PACAP (pituitary adenylate cyclase-activating polypeptide). It is composed of a 7-amino-acid sequence with a specific focus on promoting neurorestorative and neuroprotective effects. Also, This peptide has gained significant attention in the scientific community for its potential role in supporting brain health, repairing neural damage, and promoting cellular resilience.

PE-22-28 interacts with receptors in the nervous system to support various processes related to neurogenesis and cell protection. In addition, Its unique properties make it a versatile peptide for research focusing on neurological health, cognitive function, and the study of degenerative neural conditions.

PE-22-28 10mg Chemical Properties

 Effects of PE-22-28 (10mg)

Neuroprotection

PE-22-28 has demonstrated promising neuroprotective effects, helping shield neurons from oxidative stress and damage caused by toxins or trauma. This peptide may support research into therapies for neurological conditions and brain injuries.

Promotes Brain Plasticity

Studies suggest that PE-22-28 fosters neurogenesis and synaptic plasticity, critical for learning, memory, and overall cognitive function. This property has positioned it as a candidate for research into cognitive enhancement and brain recovery.

Anti-Anxiety and Mood Support

PE-22-28 has shown potential in modulating mood and reducing anxiety-like behaviors in preclinical studies. Its impact on neurotransmitter systems makes it a compelling subject for research into mood regulation.

Cellular Resilience

By interacting with cellular pathways, PE-22-28 may enhance the resilience of neural and other tissue cells against stressors, contributing to overall cellular health and recovery.

More about PE-22-28 Peptide

PE-22-28 is a synthetically produced peptide derived from spadin, a naturally occurring protein within sortilin—a key component of the central nervous system. Basically, PE-22-28 is a smaller, more concentrated form of spadin, and currently, what is known is that it operates primarily through its action upon the TREK-1 receptor. In fact, it is observed that PE-22-28 may be ” the simplest and most effective sequence for blocking the TREK-1 channel,” and more valuable as a research tool than spadin itself.

Why, then, is TREK-1 relevant? The two-pore potassium channel has been identified as one target for investigation into depression. Earlier in 2010, researchers had found that by knocking out TREK-1 receptors in mice, the mice showed increased resistance to depression behavior. Hence, TREK-1 receptors are highly prevalent in brain regions involved in mood regulation, memory, and learning, like the prefrontal cortex and the hippocampus. In simple words, stimulating TREK-1 has the effect of calming the activity of neurons, but knocking it out or impairing its function makes neurons excitable.

Also, While the majority of studies focus on its role in depression, TREK-1 may also be involved in anesthesia, pain management, and even the protection of neurons from damage. In conclusion, That’s why researchers continue to investigate its potential—PE-22-28 can be a very potent ally when it comes to researching and managing this fascinating receptor.